{"id":1527,"date":"2018-07-04T01:08:56","date_gmt":"2018-07-03T23:08:56","guid":{"rendered":"https:\/\/my-immunity.com\/staging\/?page_id=1527"},"modified":"2018-07-04T13:57:56","modified_gmt":"2018-07-04T11:57:56","slug":"phellinus-linteus-it","status":"publish","type":"page","link":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html","title":{"rendered":"Phellinus Linteus IT"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\"  style='background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;'><div class=\"fusion-builder-row fusion-row \"><div  class=\"fusion-layout-column fusion_builder_column fusion_builder_column_1_1  fusion-one-full fusion-column-first fusion-column-last 1_1\"  style='margin-top:0px;margin-bottom:20px;'>\n\t\t\t\t\t<div class=\"fusion-column-wrapper\" style=\"padding: 0px 0px 0px 0px;background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\"  data-bg-url=\"\">\n\t\t\t\t\t\t<div class=\"fusion-builder-row fusion-builder-row-inner fusion-row \"><div  class=\"fusion-layout-column fusion_builder_column fusion_builder_column_3_4  fusion-three-fourth fusion-column-first 3_4\"  style='margin-top: 0px;margin-bottom: 20px;width:75%;width:calc(75% - ( ( 4% ) * 0.75 ) );margin-right:4%;'><div class=\"fusion-column-wrapper\" style=\"padding: 0px 0px 0px 0px;background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\"  data-bg-url=\"\"><div class=\"fusion-text\"><div class=\"content-story clear-block\">\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Phellinus Linteus<\/span><\/strong><\/span><\/div>\n<p><strong>Scientific Name:<\/strong> Phellinus linteus<\/p>\n<p><strong>Common Name:<\/strong> Meshimakobu, song gen, sanghuang, sang-hwang<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-1277\" src=\"https:\/\/my-immunity.com\/staging\/wp-content\/uploads\/2018\/06\/phellinus_linteus.jpg\" alt=\"phellinus_linteus\" width=\"331\" height=\"198\" srcset=\"https:\/\/my-immunity.com\/staging\/wp-content\/uploads\/2018\/06\/phellinus_linteus-200x120.jpg 200w, https:\/\/my-immunity.com\/staging\/wp-content\/uploads\/2018\/06\/phellinus_linteus-300x179.jpg 300w, https:\/\/my-immunity.com\/staging\/wp-content\/uploads\/2018\/06\/phellinus_linteus.jpg 331w\" sizes=\"(max-width: 331px) 100vw, 331px\" \/><\/p>\n<p>Non abbiamo tradotto ma lasciato ogni pubblicazione scientifica sui funghi medicinale nella sua forma e lingua originale dal momento che tutte le informazioni provengono dal pi\u00f9 rinomato, antico e pi\u00f9 grande centro medico privato al mondo sul cancro, il <a href=\"http:\/\/www.mskcc.org\/cancer-care\/herb\/phellinus-linteus\" target=\"_blank\" rel=\"noopener\"><strong><span style=\"color: #008000;\">Memorial Sloan Kettering Cancer Center<\/span><\/strong><\/a>, che si trova a New York, fondato nel 1884.<\/p>\n<p><strong style=\"font-size: 18px;\"><span style=\"color: #008000;\">How It Works<\/span><\/strong><\/p>\n<div style=\"margin-top: 30px;\">\n<p><strong>Bottom Line: <em>Phellinus linteus<\/em> a medicinal mushroom, showed anticancer effects in lab studies. Clinical trials are needed to establish its anticancer potential.<\/strong><\/p>\n<p><em>Phellinus linteus<\/em> (PL) is a medicinal mushroom used in traditional medicine in Asia. Compounds present in this mushroom have anti-inflammatory and antitumor properties. Large scale studies are needed to confirm these effects.<\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Purported Uses<\/span><\/strong><\/span><\/div>\n<ul>\n<li><strong>To treat aging and wrinkles<\/strong><br \/>\n<em>Phellinus linteus<\/em> is used to prevent aging, and specifically to eliminate or prevent wrinkles, but research evidence is lacking.<\/li>\n<li><strong>To inhibit tumor growth<\/strong><br \/>\n<em>Phellinus linteus<\/em> has been shown in some lab studies to inhibit tumor growth but it has not been subjected to clinical trials.<\/li>\n<\/ul>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Research Evidence<\/span><\/strong><\/span><\/div>\n<p>Although PL is used as cancer treatment in Asia, large scale clinical trials are lacking. A few cases of regression of liver and prostate cancer have been reported. Such observations need to be confirmed in clinical studies.<\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Side Effects<\/span><\/strong><\/span><\/div>\n<p>PL use resulted in worsening of an autoimmune condition called pemphigus that is characterized by blisters on the skin and mucous membranes and by itching or burning.<\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Clinical Summary<\/span><\/strong><\/span><\/div>\n<p><em>Phellinus linteus<\/em> (PL) is a yellow, bitter-tasting mushroom that grows on mulberry trees. It is used in traditional medicine in Asia where it is often mixed with other medicinal mushrooms, such as <a class=\"ext\" href=\"http:\/\/www.mskcc.org\/cancer-care\/herb\/reishi-mushroom\" target=\"_blank\" rel=\"noopener\">Reishi<\/a> and <a class=\"ext\" href=\"http:\/\/www.mskcc.org\/cancer-care\/herb\/maitake\" target=\"_blank\" rel=\"noopener\">Maitake<\/a>, and promoted as an adjunctive treatment during cancer therapy. Some preparations of PL are used to prevent wrinkles and aging but clinical evidence is lacking. The polysaccharide-protein complexes found in PL were shown to have immunomodulating effects <a class=\"ext\" href=\"#references-1\"><sup>(1)<\/sup><\/a>. The polyphenolic constituent demonstrated anti-inflammatory properties, which may protect against injury and other syndromes involving infarcts, hematomas or hemorrhages in animal models <a class=\"ext\" href=\"#references-2\"><sup>(2)<\/sup><\/a> <a class=\"ext\" href=\"#references-3\"><sup>(3)<\/sup><\/a>. Other constituents, such as interfungins A, help prevent protein modification in hyperglycemic state, and may benefit diabetics <a class=\"ext\" href=\"#references-4\"><sup>(4)<\/sup><\/a>.<\/p>\n<p>PL is being researched for its potential chemoprotective effects. A number of in vitro and animal studies suggest that it has anti-angiogenic, antioxidant, and xanthine oxidase inhibition properties <a class=\"ext\" href=\"#references-5\"><sup>(5)<\/sup><\/a>. Anticancer effects against breast <a class=\"ext\" href=\"#references-6\"><sup>(6)<\/sup><\/a> <a class=\"ext\" href=\"#references-7\"><sup>(7)<\/sup><\/a> <a class=\"ext\" href=\"#references-8\"><sup>(8)<\/sup><\/a>, colon <a class=\"ext\" href=\"#references-9\"><sup>(9)<\/sup><\/a> <a class=\"ext\" href=\"#references-10\"><sup>(10)<\/sup><\/a>, liver <a class=\"ext\" href=\"#references-11\"><sup>(11)<\/sup><\/a>, lung <a class=\"ext\" href=\"#references-12\"><sup>(12)<\/sup><\/a> <a class=\"ext\" href=\"#references-13\"><sup>(13)<\/sup><\/a>, oral <a class=\"ext\" href=\"#references-14\"><sup>(14)<\/sup><\/a>, prostate <a class=\"ext\" href=\"#references-15\"><sup>(15)<\/sup><\/a> <a class=\"ext\" href=\"#references-16\"><sup>(16)<\/sup><\/a> <a class=\"ext\" href=\"#references-17\"><sup>(17)<\/sup><\/a> and skin cancers <a class=\"ext\" href=\"#references-18\"><sup>(18)<\/sup><\/a> <a class=\"ext\" href=\"#references-19\"><sup>(19)<\/sup><\/a> <a class=\"ext\" href=\"#references-1\"><sup>(1)<\/sup><\/a> have also been reported.<br \/>\nWhile there are case reports of tumor regression following consumption of PL <a class=\"ext\" href=\"#references-11\"><sup>(11)<\/sup><\/a> <a class=\"ext\" href=\"#references-20\"><sup>(20)<\/sup><\/a> <a class=\"ext\" href=\"#references-21\"><sup>(21)<\/sup><\/a>, large scale clinical studies have yet to be conducted to examine its efficacy as a cancer treatment.<\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Purported Uses<\/span><\/strong><\/span><\/div>\n<ul>\n<li>Anti-hemorrhagic<\/li>\n<li>Anti-inflammatory<\/li>\n<li>Cancer treatment and prevention<\/li>\n<\/ul>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Constituents<\/span><\/strong><\/span><\/div>\n<ul>\n<li>Protocatechuic acid<\/li>\n<li>Protocatechualdehyde<\/li>\n<li>Caffeic acid<\/li>\n<li>Ellagic acid<\/li>\n<li>Hispidin<\/li>\n<li>Davallialactone<\/li>\n<li>Hypholomine B<\/li>\n<li>Interfunging A<\/li>\n<li>Inoscavin A<\/li>\n<li>Meshimakobnol A<\/li>\n<li>Meshimakobnol B<\/li>\n<li>Phelligridin G<\/li>\n<li>Phellifuropyranone A<\/li>\n<\/ul>\n<p><a class=\"ext\" href=\"#references-4\"><sup>(4)<\/sup><\/a> <a class=\"ext\" href=\"#references-22\"><sup>(22)<\/sup><\/a><\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Mechanism of Action<\/span><\/strong><\/span><\/div>\n<p>The polysaccharide-protein complexes found in PL have immunomodulating <a class=\"ext\" href=\"#references-1\"><sup>(1)<\/sup><\/a>, anti-angiogenic, and antioxidant and xanthine oxidase inhibition effects <a class=\"ext\" href=\"#references-5\"><sup>(5<\/sup><\/a>). Additionally, the furopyranone compounds inhibit protein glycation, which may aid in treatment and prevention of diabetic complications <a class=\"ext\" href=\"#references-4\"><sup>(4)<\/sup><\/a> <a class=\"ext\" href=\"#references-23\"><sup>(23)<\/sup><\/a>. In non-obese diabetic mice, a polysaccharide extract from PL enhanced function of macrophages, dendritic cells, NK cells, T cells and B cells, prevented inflammation by inhibiting IFN-gamma, IL-2 and TNF-alpha by TH1 cells and macrophages; it also upregulated IL-4 expression in TH2 cells. These effects may help prevent diabetes <a class=\"ext\" href=\"#references-23\"><sup>(23)<\/sup><\/a>. The anti-inflammatory activities of inotilone, a compound isolated from PL might be due to reduced levels of malondialdehyde (MDA), inducible nitric oxide synthase (iNOS), COX-2, NF-\u03baB, and matrix metalloproteinase (MMP)-9, and via increased activities of catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) through the suppression of TNF-\u03b1 and nitric oxide (NO) <a class=\"ext\" href=\"#references-25\"><sup>(25)<\/sup><\/a>. In another study, hispidin, a phenolic compound present in PL, was shown to protect against peroxynitrite-mediated cytotoxicity, DNA damage and hydroxyl radical formation <a class=\"ext\" href=\"#references-26\"><sup>(26)<\/sup><\/a>.<\/p>\n<p>PL also inhibited proliferation of SW480, a human colon cancer cell line via decreasing Bcl-2 and cyclin B1, and increasing cytochrome C <a class=\"ext\" href=\"#references-9\"><sup>(9)<\/sup><\/a>. Another study similarly found that a PL extract induced G0\/G1 arrest and apoptosis in human colon carcinoma HT29 cells, through p21(C1P1\/WAF1) upregulation, cyclin D1 downregulation, Bcl2 downregulation, release of cytochrome C and activation of caspases 9, 3 and 8 <a class=\"ext\" href=\"#references-10\"><sup>(10)<\/sup><\/a>. Decrease in cyclin-dependent kinases CDK2, 4 and 6, and dose-dependent apoptosis of lung cancer cells after treatment with PL were also observed <a class=\"ext\" href=\"#references-12\"><sup>(12)<\/sup><\/a>. Further, it suppressed aryl hydrocarbon receptor activity and AhR-dependent gene expression, both pathways activated by cigarette smoking <a class=\"ext\" href=\"#references-13\"><sup>(13)<\/sup><\/a>.<\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">Adverse Reactions<\/span><\/strong><\/span><\/div>\n<p>Exacerbation of pemphigus (an autoimmune disorder) was reported following use of PL <a class=\"ext\" href=\"#references-24\"><sup>(24)<\/sup><\/a>.<\/p>\n<p><span style=\"color: #008000;\"><strong><u>Purpose of this published study is scientific information and education, it should not be used for diagnosing or treating a health problem or disease. This website is designed for general education and information purposes only and does not substitute for professional medical advice, examination, diagnosis or treatment.<\/u><\/strong><\/span><\/p>\n<div><span style=\"font-size: 18px;\"><strong><span style=\"color: #008000;\">References<\/span><\/strong><\/span><\/div>\n<p><span style=\"color: #008000;\"><em><strong>Source of Information: <a href=\"http:\/\/www.mskcc.org\/cancer-care\/herb\/phellinus-linteus\" target=\"_blank\" rel=\"noopener\">Memorial Sloan Kettering Cancer Center<\/a>, the oldest and largest private cancer center, located in New York, founded in 1884.<\/strong><\/em><\/span><\/p>\n<ol>\n<li>Kim GY LJ, Lee JO, Ryu CH, Choi BT, Jeong YK, Lee KW, Jeong SC, Choi YH. <a name=\"references-1\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16717425\" target=\"_blank\" rel=\"noopener\">Partial characterization and immunostimulatory effect of a novel polysaccharide-protein complex extracted from Phellinus linteus<\/a>. <em>Biosci Biotechnol Biochem<\/em>. May 2006;70(5):1218-1226.<\/li>\n<li>Chang HY SM, Yang CH, Lu TC, Chang YS, Peng WH, Huang SS, Huang GJ. <a name=\"references-2\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19349477\" target=\"_blank\" rel=\"noopener\">Analgesic Effects and the Mechanisms of Anti-Inflammation of Hispolon in Mice<\/a>. <em>Evid Based Complement Alternat Med<\/em>. Apr 6. 2009<\/li>\n<li>Suzuki S KT, Okada Y, Kobayashi T, Nakamura T, Hori T. <a name=\"references-3\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19155273\" target=\"_blank\" rel=\"noopener\">Filtrate of Phellinus linteus Broth Culture Reduces Infarct Size Significantly in a Rat Model of Permanent Focal Cerebral Ischemia<\/a>. <em>Evid Based Complement Alternat Med<\/em>. Jan 20. 2009.<\/li>\n<li>Lee YS KY, Jung JY, Lee S, Ohuchi K, Shin KH, Kang IJ, Park JH, Shin HK, Lim SS. <a name=\"references-4\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18827365\" target=\"_blank\" rel=\"noopener\">Protein glycation inhibitors from the fruiting body of Phellinus linteus<\/a>. <em>Biol Pharm Bull<\/em>. Oct 31 2008;31(10):1968-1972.<\/li>\n<li>Song YS, Kim SH, Sa JH, Jin C, Lim CJ, Park EH. <a name=\"references-5\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12902060\" target=\"_blank\" rel=\"noopener\">Anti-angiogenic, antioxidant and xanthine oxidase inhibition activities of the mushroom Phellinus linteus<\/a>. J <em>Ethnopharmacol<\/em>. Sep 2003;88(1):113-116.<\/li>\n<li>Sliva D, Jedinak A, Kawasaki J, Harvey K, Slivova V. <a name=\"references-6\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18362935\" target=\"_blank\" rel=\"noopener\">Phellinus linteus suppresses growth, angiogenesis and invasive behaviour of breast cancer cells through the inhibition of AKT signalling<\/a>. <em>Br J Cancer<\/em>. 2008 Apr 22;98(8):1348-56.<\/li>\n<li>Lu TL HG, Lu TJ, Wu JB, Wu CH, Yang TC, Iizuka A, Chen YF. <a name=\"references-7\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19477214\" target=\"_blank\" rel=\"noopener\">Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1\/2 activity in breast and bladder cancer cells<\/a>. <em>Food Chem Toxicol<\/em>. Aug 2009;47(8):2013-2021.<\/li>\n<li>Sliva D JA, Kawasaki J, Harvey K, Slivova V. <a name=\"references-8\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18362935\" target=\"_blank\" rel=\"noopener\">Phellinus linteus suppresses growth, angiogenesis and invasive behaviour of breast cancer cells through the inhibition of AKT signalling<\/a>. <em>Br J Cancer<\/em>. Apr 22 2008;98(8):1348-1356.<\/li>\n<li>Li G KD, Kim TD, Park BJ, Park HD, Park JI, Na MK, Kim HC, Hong ND, Lim K, Hwang BD, Yoon WH. <a name=\"references-9\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15533593\" target=\"_blank\" rel=\"noopener\">Protein-bound polysaccharide from Phellinus linteus induces G2\/M phase arrest and apoptosis in SW480 human colon cancer cells<\/a>. <em>Cancer Lett<\/em>. Dec 28 2004;216(2):175-181.<\/li>\n<li>Park HJ CS, Hong SM, Hwang SG, Park DK. <a name=\"references-10\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19998418\" target=\"_blank\" rel=\"noopener\">The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G(0)\/G(1) cell cycle arrest and apoptosis in human colon carcinoma HT29 cells<\/a>. <em>Phytother Res<\/em>. 2010 Jul;24(7):1019-26.<\/li>\n<li>Nam SW, Han JY, Kim JI, et al. <a name=\"references-11\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15740500\" target=\"_blank\" rel=\"noopener\">Spontaneous regression of a large hepatocellular carcinoma with skull metastasis<\/a>. <em>J Gastroenterol Hepatol<\/em>. Mar 2005;20(3):488-492.<\/li>\n<li>Guo J ZT, Collins L, Xiao ZX, Kim SH, Chen CY. <a name=\"references-12\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17131292\" target=\"_blank\" rel=\"noopener\">Modulation of lung cancer growth arrest and apoptosis by Phellinus Linteus<\/a>. Mol Carcinog. Feb 2007;46(2):144-154.<\/li>\n<li>Mukai M KA, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Yao J, Nakamura T, Kitamura M. <a name=\"references-13\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18827349\" target=\"_blank\" rel=\"noopener\">Blockade of the aryl hydrocarbon receptor pathway triggered by dioxin, polycyclic aromatic hydrocarbons and cigarette smoke by Phellinus linteus<\/a>. <em>Biol Pharm Bull<\/em>. Oct 2008;31(10):1888-1893.<\/li>\n<li>Chen W HF, Li YQ. <a name=\"references-14\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16563677\" target=\"_blank\" rel=\"noopener\">The apoptosis effect of hispolon from Phellinus linteus (Berkeley &amp; Curtis) Teng on human epidermoid KB cells<\/a>. <em>J Ethnopharmacol<\/em>. Apr 21 2006;105(1-2):280-285.<\/li>\n<li>Collins L ZT, Guo J, Xiao ZJ, Chen CY. <a name=\"references-15\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16868541\" target=\"_blank\" rel=\"noopener\">Phellinus linteus sensitises apoptosis induced by doxorubicin in prostate cancer<\/a>. <em>Br J Cancer<\/em>. Aug 7 2006;95(3):282-288.<\/li>\n<li>Tsuji T DW, Nishioka T, Chen L, Yamamoto D, Chen CY. <a name=\"references-16\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20360989\" target=\"_blank\" rel=\"noopener\">Phellinus linteus extract sensitizes advanced prostate cancer cells to apoptosis in athymic nude mice<\/a>. <em>PLoS One<\/em>. Mar 31 2010;5(3):e9885.<\/li>\n<li>Zhu T GJ, Collins L, Kelly J, Xiao ZJ, Kim SH, Chen CY. <a name=\"references-17\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17262078\" target=\"_blank\" rel=\"noopener\">Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells<\/a>. <em>Br J Cancer<\/em>. Feb 26 2007;96(4):583-590.<\/li>\n<li>Han SB LC, Kang JS, Yoon YD, Lee KH, Lee K, Park SK, Kim HM. <a name=\"references-18\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16504934\" target=\"_blank\" rel=\"noopener\">Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion<\/a>. <em>Int Immunopharmacol<\/em>. Apr 2006;6(4):697-702.<\/li>\n<li>Lee HJ LH, Lim ES, Ahn KS, Shim BS, Kim HM, Gong SJ, Kim DK, Kim SH. <a name=\"references-19\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15635158\" target=\"_blank\" rel=\"noopener\">Cambodian Phellinus linteus inhibits experimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator<\/a>. <em>Biol Pharm Bull<\/em>. Jan 2005;28(1):27-31.<\/li>\n<li>Shibata Y, Kurita S, Okugi H, Yamanaka H. <a name=\"references-20\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15331908\" target=\"_blank\" rel=\"noopener\">Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus<\/a>. <em>Urol Int<\/em>. 2004;73(2):188-190.<\/li>\n<li>Kojima H TN, Kariya S, Komemushi A, Shomura Y, Sawada S, Arai E, Yokota Y. <a name=\"references-21\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16715676\" target=\"_blank\" rel=\"noopener\">A case of spontaneous regression of hepatocellular carcinoma with multiple lung metastases<\/a>. Radiat Med. Feb 2006;24(2):139-142.<\/li>\n<li>Kojima K OT, Inoue M, Mizukami H, Nagatsu A. <a name=\"references-22\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18239302\" target=\"_blank\" rel=\"noopener\">Phellifuropyranone A: a new furopyranone compound isolated from fruit bodies of wild Phellinus linteus<\/a>. <em>Chem Pharm Bull (Tokyo)<\/em>. Feb 2008;56(2):173-175.<\/li>\n<li>Kim HM KJ, Kim JY, Park SK, Kim HS, Lee YJ, Yun J, Hong JT, Kim Y, Han SB. <a name=\"references-23\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19811769\" target=\"_blank\" rel=\"noopener\">Evaluation of antidiabetic activity of polysaccharide isolated from Phellinus linteus in non-obese diabetic mouse<\/a>. <em>Int Immunopharmacol<\/em>. Jan 2010;10(1):72-78.<\/li>\n<li>Jin SP, Hong JS, Chung JH. <a name=\"references-24\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20561124\" target=\"_blank\" rel=\"noopener\">Exacerbation of pemphigus following Phellinus linteus ingestion<\/a>. <em>J Eur Acad Dermatol Venereol<\/em>. 2011 Apr;25(4):492-3.<\/li>\n<li>Huang GJ, Huang SS, Deng JS. <a name=\"references-25\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22590514\" target=\"_blank\" rel=\"noopener\">Anti-inflammatory activities of inotilone from Phellinus linteus through the inhibition of MMP-9, NF-\u03baB, and MAPK activation in vitro and in vivo.<\/a><em>PLoS One. <\/em>2012;7(5):e35922.<\/li>\n<li>Chen W, Feng L, Huang Z, Su H. <a name=\"references-26\"><\/a><a class=\"ext\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22819952\" target=\"_blank\" rel=\"noopener\">Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.<\/a><em>Chem Biol Interact.<\/em> 2012 Sep 30;199(3):137-42.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><div  class=\"fusion-layout-column fusion_builder_column fusion_builder_column_1_4  fusion-one-fourth fusion-column-last 1_4\"  style='margin-top: 0px;margin-bottom: 20px;width:25%;width:calc(25% - ( ( 4% ) * 0.25 ) );'><div class=\"fusion-column-wrapper\" style=\"padding: 0px 0px 0px 0px;background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\"  data-bg-url=\"\"><div class=\"fusion-widget-area fusion-widget-area-1 fusion-content-widget-area\"><style type=\"text\/css\" scoped=\"scoped\">.fusion-widget-area-1 {padding:0px 0px 0px 0px;}.fusion-widget-area-1 .widget h4 {color:#333333;}.fusion-widget-area-1 .widget .heading h4 {color:#333333;}<\/style>\n\t\t<section id=\"recent-posts-2\" class=\"widget widget_recent_entries\">\n\t\t<div class=\"heading\"><h4 class=\"widget-title\">\u0421\u043a\u043e\u0440\u0430\u0448\u045a\u0438 \u0447\u043b\u0430\u043d\u0446\u0438<\/h4><\/div>\n\t\t<ul>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t<a href=\"https:\/\/my-immunity.com\/staging\/immunotherapy.html\">Immunotherapy &#8211; the next generation of cancer treatment<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t<a href=\"https:\/\/my-immunity.com\/staging\/es\/cu%c3%a1les-son-los-componentes-del-sistema-inmune.html\">\u00bfCu\u00e1les son los componentes del sistema inmune?<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t<a href=\"https:\/\/my-immunity.com\/staging\/es\/atp-molecula-que-lleva-la-energia-de-la-vida.html\">ATP mol\u00e9cula que lleva la &#8222;energ\u00eda de la vida&#8220;<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t<a href=\"https:\/\/my-immunity.com\/staging\/ru\/%d1%87%d1%82%d0%be-%d1%82%d0%b0%d0%ba%d0%be%d0%b5-%d0%bc%d0%b5%d0%b4%d0%b8%d1%86%d0%b8%d0%bd%d1%81%d0%ba%d0%b8%d0%b5-%d0%b3%d1%80%d0%b8%d0%b1%d1%8b.html\">\u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0435 \u0433\u0440\u0438\u0431\u044b<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t<a href=\"https:\/\/my-immunity.com\/staging\/ru\/%d0%ba%d0%b0%d0%ba-%d0%bf%d1%80%d0%be%d0%b8%d1%81%d1%85%d0%be%d0%b4%d0%b8%d1%82-%d0%b1%d0%be%d0%bb%d0%b5%d0%b7%d0%bd%d1%8c.html\">\u041a\u0430\u043a \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0434\u0438\u0442 \u0431\u043e\u043b\u0435\u0437\u043d\u044c<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\n\t\t<\/section><section id=\"text-2\" class=\"widget widget_text\" style=\"border-style: solid;border-color:transparent;border-width:0px;\">\t\t\t<div class=\"textwidget\"><p>Aloha Medicinals proizvode mo\u017eete poru\u010diti putem pouze\u0107a na:<\/p>\n<p>tel: <strong>011\/ 25 46 452 i 062\/ 55 77 12<\/strong><\/p>\n<p>Tro\u0161kove dostave pla\u0107amo mi, osim kod ponude 3+1 gratis, gde tro\u0161kove dostave pla\u0107a kupac.<\/p>\n<p><strong>MOJ IMUNITET D.O.O. 11000 Beograd Tel: 011\/ 25 46 452 i 062\/ 55 77 12<\/strong><\/p>\n<p>&nbsp;<\/p>\n<\/div>\n\t\t<\/section><div class=\"fusion-additional-widget-content\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div>\n\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Phellinus Linteus IT - My immunity<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html\" \/>\n<meta property=\"og:locale\" content=\"sr_RS\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Phellinus Linteus IT - My immunity\" \/>\n<meta property=\"og:url\" content=\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html\" \/>\n<meta property=\"og:site_name\" content=\"My immunity\" \/>\n<meta property=\"article:modified_time\" content=\"2018-07-04T11:57:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/my-immunity.com\/staging\/wp-content\/uploads\/2018\/06\/phellinus_linteus.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u041f\u0440\u043e\u0446\u0435\u045a\u0435\u043d\u043e \u0432\u0440\u0435\u043c\u0435 \u0447\u0438\u0442\u0430\u045a\u0430\" \/>\n\t<meta name=\"twitter:data1\" content=\"10 \u043c\u0438\u043d\u0443\u0442\u0430\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html\",\"url\":\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html\",\"name\":\"Phellinus Linteus IT - My immunity\",\"isPartOf\":{\"@id\":\"https:\/\/my-immunity.com\/staging\/#website\"},\"datePublished\":\"2018-07-03T23:08:56+00:00\",\"dateModified\":\"2018-07-04T11:57:56+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html#breadcrumb\"},\"inLanguage\":\"sr-RS\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/my-immunity.com\/staging\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Phellinus Linteus IT\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/my-immunity.com\/staging\/#website\",\"url\":\"https:\/\/my-immunity.com\/staging\/\",\"name\":\"My immunity\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/my-immunity.com\/staging\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sr-RS\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Phellinus Linteus IT - My immunity","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html","og_locale":"sr_RS","og_type":"article","og_title":"Phellinus Linteus IT - My immunity","og_url":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html","og_site_name":"My immunity","article_modified_time":"2018-07-04T11:57:56+00:00","og_image":[{"url":"https:\/\/my-immunity.com\/staging\/wp-content\/uploads\/2018\/06\/phellinus_linteus.jpg"}],"twitter_card":"summary_large_image","twitter_misc":{"\u041f\u0440\u043e\u0446\u0435\u045a\u0435\u043d\u043e \u0432\u0440\u0435\u043c\u0435 \u0447\u0438\u0442\u0430\u045a\u0430":"10 \u043c\u0438\u043d\u0443\u0442\u0430"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html","url":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html","name":"Phellinus Linteus IT - My immunity","isPartOf":{"@id":"https:\/\/my-immunity.com\/staging\/#website"},"datePublished":"2018-07-03T23:08:56+00:00","dateModified":"2018-07-04T11:57:56+00:00","breadcrumb":{"@id":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html#breadcrumb"},"inLanguage":"sr-RS","potentialAction":[{"@type":"ReadAction","target":["https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/my-immunity.com\/staging\/it\/phellinus-linteus-it.html#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/my-immunity.com\/staging\/"},{"@type":"ListItem","position":2,"name":"Phellinus Linteus IT"}]},{"@type":"WebSite","@id":"https:\/\/my-immunity.com\/staging\/#website","url":"https:\/\/my-immunity.com\/staging\/","name":"My immunity","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/my-immunity.com\/staging\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sr-RS"}]}},"_links":{"self":[{"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/pages\/1527"}],"collection":[{"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/comments?post=1527"}],"version-history":[{"count":2,"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/pages\/1527\/revisions"}],"predecessor-version":[{"id":1539,"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/pages\/1527\/revisions\/1539"}],"wp:attachment":[{"href":"https:\/\/my-immunity.com\/staging\/wp-json\/wp\/v2\/media?parent=1527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}